Image Biopsy Lab (IB Lab) addresses existing problems in the assessment and tracking of osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP). For this purpose, IB Lab provides for the first time an objective evaluation and follow up of the knee joint on the basis of selected parameters (IB Lab JSxTM). In addition, applying a combination of bone micro architecture algorithms provides a unique way of an in-depth diagnosis of the condition of the bone (IB Lab BMAxTM).